Design of Functional Biomaterials for Soft Tissue Repair

Current biomaterials design strategies are focused on developing biocompatible or bioinert materials that are expected to elicit minimal adverse biological responses at the implant site. Although such biomaterials are useful however don’t have the capacity to improve or restore tissue or organ function. Also, the cellular and molecular responses affect the long-term success of the biomaterials. We herein present the design and fabrication of functional biomaterials encoded with immunomodulatory and regenerative attributes to reorient the tissue microenvironment towards regenerative wound repair. Further, utility of these functional biomaterials as surgical implants and in soft tissue repair will be presented.