Paradigm Shift in Treatment Design for Movement Disorders Using Personalized Neuromusculoskeletal Models

Osteoarthritis, stroke, spinal cord injury, cerebral palsy, Parkinson’s disease, and amputation significantly impair human movement. These conditions result in an increased risk of health consequences such as heart disease and diabetes, in addition to societal costs. Nonetheless, treatment design for movement impairments has not progressed considerably. In order to regain patients’ maximum function, a paradigm shift from subjective clinical judgment toward personalized treatments taking advantage of objective methods is needed.